José graduated in Technological Physics Engineering from Instituto Superior Técnico, Technical University of Lisbon in 1999 and joined the lab of Prof. Maria Carmo-Fonseca at the Faculty of Medicine, University of Lisbon in the same year for his PhD, which was focused on the study of dynamics and interactions of nuclear proteins with quantitative photobleaching microscopy.
José completed his PhD in Biophysics in 2007 from the Faculty of Sciences, University of Lisbon. His postdoctoral research, carried out at the Instituto de Medicina Molecular (IMM) focused on applying quantitative microscopy methods to study mRNA biogenesis. In 2009, José was hired under the Ciência 2008 program by the IMM as Head of the Bioimaging Unit, the core microscope facility of the Institute. Between 2013 and 2016 José was also responsible for the Optical Imaging and Microscopy Platform of the Champalimaud Centre for the Unknown, Lisbon. In 2016 José was also appointed by the IMM as Head of the Flow Cytometry Facility.